Global economy has always suffered from different crises which influence economy's real variables, including capital market indices. International financial crisis initiated aftermath of the burst of the housing bubble in the credit division in the U.S.A. and reached the highest level by the bankruptcy of some banks in the financial markets and then penetrated into the economy's real divisions including stock exchange. In the current study the impact of this crisis on Tehran Stock Exchange is examined using Auto Regressive Distributed Lag model on a seasonally basis from spring of 1998 to winter of 2008. The results show that the liquidity variables and the exchange rates with a period of interval and the bank interest rate in the same period hold a direct relationship with Tehran Stock Exchange. But the financial crisis has a negative impact on this relationship which is in accordance with the reality and requires strategies to be taken in order to defeat the crisis.